Beta-D-Glucan Antigen

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The Fungitell® assay measures the presence of (1→3)-β-D-Glucan in serum and CSF. Serum is the only specimen type cleared by the FDA for this assay. Performance characteristics of CSF have been validated by MiraVista Diagnostics.

Colorimetric Fungitell® assay utilizing a (1→3)-β-D-Glucan -specific Limulus Amebocyte Lysate (LAL) reagent.

Interfering Substance: Turbid or grossly discolored samples due to lipid, bilirubin, or hemolysis. Significantly elevated immunoglobulin concentrations.

• Hemodialysis
• Penicillin antibiotics
• Fractionated blood products (serum albumin and immunoglobulins)
• Specimens exposed to gauze or paper wipes

Testing is performed Monday – Friday.

Results released:  24 – 48 hours

None detected

Negative: <60 pg/mL
Indeterminate: 60 pg/mL – 79 pg/mL
Positive: 80 pg/mL – >500 pg/mL

* Fungitell® is a registered trademark of Associates of Cape Cod Inc.

Specimen:  Serum, CSF

Container:
Serum: Collect serum specimens in serum separator tube. Allow blood to clot for 30 minutes, then centrifuge. Send in serum separator tube or pipette serum into a transport tube
CSF: Submit CSF in a sterile leak-proof plastic tube.

Volume:  0.25 mL
Stability: Refrigerated = 5 days; Frozen = indefinite

Turbid or grossly discolored samples due to lipid, bilirubin, or hemolysis or significantly elevated immunoglobulin concentrations may be rejected due to interference.

Refrigerated/Frozen

Ship overnight with a cold pack.