Oklahoma State University Veterinary Medical Hospital Seeks Participants for Genetic Study of Histoplasma Capsulatum

In conjunction with the CDC, this genetic study will investigate the genetic make-up of Histoplasma capsulatum causing disease in dogs and cats.

Clinical Study

Histoplasmosis is a relatively common and life-threatening disease in dogs and cats in OK and surrounding states. Histoplasmosis is a fungal infection caused by H. capsulatumH. capsulatum is found around the world and has traditionally been separated into three varieties based on geographic location.  More recently, genetic studies have shown that there are more varieties than once thought.

In conjunction with the CDC, this genetic study will investigate the genetic make-up of Histoplasma capsulatum causing disease in dogs and cats. Understanding the genetic make-up of H. capsulatum is very important as it might affect characteristics such as which dogs or cats are at risk, where the infection might spread, the severity of infection and how the disease might respond to treatment.  In addition, this study might help develop prevention strategies in both animals and humans.  This study will non-invasively collect samples from dogs and cats with histoplasmosis and investigate the genetic make-up of the infecting H. capsulatum organisms. There are financial incentives for study involvement.

Eligible Candidates

Any dog or cat that has confirmed histoplasmosis (based on identification of Histoplasma yeasts on cytology, histopathology, or culture) is a candidate.

Contact

For more information or to refer a patient for possible inclusion in this clinical study, please contact Dr. Andrew Hanzlicek at the Oklahoma State University Veterinary Medical Hospital at 405-744-7000 or email andrew.hanzlicek@okstate.edu.

To learn more about this genetic study of Histoplasma capsulatum, please visit https://cvhs.okstate.edu/research/clinical-trials/small-animal/index.html

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