Histoplasma Antigen EIA

  • Test Information
  • Specimen Requirements
  • Shipping Information
  • Test Code+-


    Clinical Significance+-

    The MVista® Histoplasma Quantitative EIA test aids in the diagnosis of histoplasmosis. Monitoring the Histoplasma antigen helps to determine when treatment can be stopped and to diagnose relapse.


    • Quantitative Sandwich Enzyme Immunoassay (EIA)
    • Serum and CSF are pre-treated to improve accuracy


    The result is not intended to be used as the sole means for clinical diagnosis or patient management decisions.

    Cross Reactivity/False Positive:
    • Very High: Blastomyces, Histoplasma, Paracoccidioides and Talaromyces (talaromycosis, previously penicilliosis)
    • Moderate: Coccidioides
    • Rare: Aspergillus
    • None: Cryptococcus
    • Sputolysin, sodium hydroxide and potassium hydroxide treatment degrade the analyte detected in the assay.

    Turnaround Time+-

    Testing is performed Monday – Saturday.

    Results released: 24 – 48 hours

    *New positives may require confirmation

    Reference Range+-

    None detected

    Interpretative Information+-

    EIA New Test Parameters

    • Reference Interval: None Detected
    • Reportable Range: 0.2 ng/ml – 20.0 ng/ml
    • Results above 20.0 ng/ml are reported as Positive, Above the Limit of Qualification

    Additional Information+-

    MVista® is a registered trademark of MiraVista Diagnostics

  • Specimen Collection+-

    Specimen: Urine, Serum, Plasma, CSF, BAL

    Serum: Collect serum specimens in serum separator tube. Allow blood to clot for 30 minutes, then centrifuge. Send serum in serum separator tube or transfer tube.
    Plasma: Collect plasma specimens in an EDTA, heparin or sodium citrate tube. Centrifuge for 15 minutes and pipette plasma into a plastic screw cap vial.
    Urine/CSF/BAL/Other Body Fluids: Submit urine, CSF, BAL and all other body fluids in a leak-proof container.

    Volume: Serum/Plasma 1.2 mL, CSF 0.8 mL, Urine and BAL 0.5 mL
    Stability: Room Temperature=2 weeks, Refrigerated=2 weeks, Frozen=indefinite

    Specimen Rejection+-

    • If specimen is too viscous to pipette
    • Tissue, Sputum, Bronchial Brushings, Stool, FNA, Biopsy, Tracheal or Bone Marrow Aspirate
    • Stored in Transport Media, Fixative or Isolator Tubes
  • Transport Temperature+-

    Refrigerated/Frozen/Room Temperature


    Ship Overnight or 2nd day ambient