Coccidioides Canine Antibody IgG EIA
- Test Information
- Specimen Requirements
- Shipping Information
Test Code
329
Clinical Significance
The presence of IgG to Coccidioides assists in the diagnosis of coccidioidomycosis in dogs. IgG may be detected in some healthy dogs from the endemic area as a result of sub-clinical infection within the last 2 years. Intermediate results (8-9.9 EU) typically reflect either rising or falling IgG, and retesting the patient in several weeks may be beneficial.
Methodology
Semi-Quantitative Indirect Enzyme Immunoassay (EIA)
Limitations
Cross-reactivity/False Positives: Low: Histoplasma and Blastomyces (true positives are considerably higher than cross-reactive results)
The reference range and other method performance specifications have not been established for this test in CSF. The test results should be integrated into the clinical context for interpretation.
Turnaround Time
Results Released: 24-48 hours
Reference Range
Negative
Interpretative Information
Negative: <8.0 EU
Intermediate: 8.0 – 9.9 EU
Positive: 10.0 – ≥80.0 EUSpecimen Collection
- Specimen: Serum
- Uncommon Specimen: CSF, Plasma
Anticoagulant: Heparin, EDTA, NaCit
Container:
- Serum: Submit serum in a separator or transfer tube.
- CSF/Plasma: Submit CSF/Plasma in a sterile leak-proof container.
Minimum Specimen Requirements
Volume: 0.25 mL
Specimen Stability
- Room temperature: 28 days
- Refrigerated: 6 months
- Frozen: indefinite
Specimen Rejection
Any specimen types other than serum, plasmacerebrospinal fluid or if specimen exceeds stated stability ranges.
Transport Temperature
Refrigerated/Frozen
Shipping
Overnight or 2nd day – ambient or with cold pack.
* New positives may require confirmation.
** Turnaround times are provided as ranges, and may vary depending on daily testing volumes and specimen type.
*** Test set up: Samples received by 10:30AM will have same-day test set up. Positive samples may require confirmation which may extend turnaround time. Serum & CSF specimens are pretreated to improve sensitivity which can add one day to turnaround time.