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The MVista® Itraconazole bioassay test aids in monitoring antifungal therapy.
Bioassay
The result is not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Interfering Substance: Other antifungals can cause falsely high results. Stop these at least 1 week before obtaining sample.
Testing performed on Wednesday.
Results released: 24 hours
Recommended therapeutic range is 2.0 – 7.0 µg/mL
None Detected: Reported when there is no zone of inhibition.
<0.3 µg/mL: Reported when the zone of inhibition is smaller than that of the lowest calibrator.
Positive: 0.3 – 20.0 µg/mL
>20.0 µg/mL: Reported when the zone of inhibition is greater than the highest calibrator.
Drug levels should be measured after steady-state (at least 2 weeks in dogs & 3 weeks in cats). It is recommended, but not required (due to long half-life), to collect blood sample at trough time (as close to next dose as possible).
Specimen: Serum
Container:
Serum: Collect serum specimens in serum separator tube. Allow blood to clot for 30 minutes, then centrifuge. Send serum in serum separator tube or transfer tube
Volume: 0.25mL
Stability: Room temperature = 7 days, Refrigerated = 7 days, Frozen = 7 days
Any specimen type other than serum.
Refrigerated/Frozen
Ship overnight or 2nd day – ambient or with cold pack.