Aspergillus Antibody Immunodiffusion

  • Test Information
  • Specimen Requirements
  • Shipping Information
  • Test Code+-

    324

    Clinical Significance+-

    The Aspergillus Antibody Immunodiffusion test is used for the in vitro determination of precipitating antibodies to Aspergillus spp. The test is most useful in assisting with the diagnosis of sino-nasal aspergillosis in dogs.

    Methodology+-

    Fungal Immunodiffusion

    Limitations+-

    The result is not intended to be used as the sole means for clinical diagnosis or patient management decisions.

    • Negative serologic tests may be observed among culturally demonstrable cases, which limits the predictive value of a negative test.
    • Negative serologic results obtained during the first month may warrant repeat testing.
    • Falsely negative results may be obtained when testing immunocompromised patients.
    • Test results cannot be used solely to distinguish between active infection and prior exposure.
    • C-Reactive Protein present in the patient’s serum may interfere with interpretation of results.

    Cross Reactivity/False Positive: Moderate to Low: Blastomyces, Histoplasma, and Coccidioides

    Turnaround Time+-

    Testing performed Tuesday and Friday.
    Results Released: Positive: 24 hours; Negative: 72 hours.

    Reference Range+-

    Antibody not detected

    Interpretative Information+-

    Negative: Antibody not detected
    Positive: Antibody detected

  • Specimen Collection+-

    Specimens:  Serum, CSF*, Plasma*
    *Uncommon specimen includes incomplete validation. A “rare specimen” note will appear on the final report.

    Container:
    Serum: Collect serum specimens in serum separator tube. Allow blood to clot for 30 minutes, then centrifuge. Send in serum separator tube or transfer tube.
    CSF, Plasma: Submit CSF and plasma in a leak-proof plastic tube.

    Volume: 0.25mL
    Stability: Room temperature = 28 days, Refrigerated = 6 months, Frozen = indefinite

    Specimen Rejection+-

    Any specimen types other than serum, CSF, plasma

  • Transport Temperature+-

    Refrigerated/Frozen

    Shipping+-

    Ship overnight with a cold pack.

CREDENTIALS:
CREDENTIALS: