Medical-Diagnostics
Medical-Diagnostics

DIAGNOSTIC TESTS

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Aspergillus Antigen EIA

  • Test Information
  • Specimen Requirements
  • Shipping Information

  • Test Code +

    309

    Clinical Significance +

    The Aspergillus Antigen EIA test aids in the diagnosis of systemic aspergillosis in animals. This test has low sensitivity in dogs with sino-nasal aspergillosis; therefore, the test is not recommended for screening in those cases.

    Methodology +

    Platelia™ Aspergillus EIA immunoenzymatic sandwich microplate assay, cleared by the FDA for the detection of galactomannan in serum or BALF.

    Limitations +

    The result is not intended to be used as the sole means for clinical diagnosis or patient management decisions.

    • Antifungal therapy may cause false negative results in patients with aspergillosis.
    • Low positive results (0.5-1.5 GMI) are equivocal and may represent false positives, as the cutoff of 0.5 GMI was determined based on human studies for the early diagnosis of invasive fungal infections.
    Cross Reactivity/False Positive:
    • Certain gluconate containing fluids (Vetivex pHLyte NOT Plasmalyte or Norm-R)
    • Potentially penicillin antibiotics
    • High: Alternaria, Fusarium, Geotrichum, Paecilomyces
    • Low: Coccidioides, Cryptococcus, Blastomyces, Histoplasma

    Turnaround Time +

    Test Setup:  Monday – Friday
    Urine/Serum/CSF/BAL: Results Released in 24 – 48 hours

    *New positives may require confirmation

    Reference Range +

    Negative

    Interpretative Information +

    Negative: <0.5

    *Results are reported as numeric values (Index) which are interpreted as positive or negative.

    Additional Information +

    Platelia™ is a registered trademark of BioRad.

  • Specimen Collection +

    Specimen: Urine, Serum, CSF, BAL

    Container:
    Serum: Collect serum specimens in serum separator tube. Allow blood to clot for 30 minutes, then centrifuge. Send serum in serum separator tube or transfer tube.
    Urine/CSF/BAL: Submit Urine, CSF, and BAL in a sterile leak proof plastic tube.

    Volume: 0.8mL
    Stability: Room temperature = 48 hours; Refrigerated = 5 days; Frozen = 5 months

    Specimen Rejection +

    If specimen is too viscous to pipette.

  • Transport Temperature +

    Refrigerated/Frozen

    Shipping +

    Ship overnight or 2nd day-ambient or with cold pack.

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