Aspergillus Antibody Immunodiffusion
- Test Information
- Specimen Requirements
- Shipping Information
Test Code
324
Clinical Significance
The Aspergillus Antibody Immunodiffusion test is used for the in vitro determination of precipitating antibodies to Aspergillus spp. The test is most useful in assisting with the diagnosis of sino-nasal aspergillosis in dogs.
Methodology
Fungal Immunodiffusion
Limitations
The result is not intended to be used as the sole means for clinical diagnosis or patient management decisions.
- Negative serologic tests may be observed among culturally demonstrable cases, which limits the predictive value of a negative test.
- Negative serologic results obtained during the first month may warrant repeat testing.
- Falsely negative results may be obtained when testing immunocompromised patients.
- Test results cannot be used solely to distinguish between active infection and prior exposure.
- C-Reactive Protein present in the patient’s serum may interfere with interpretation of results.
Cross Reactivity/False Positive: Moderate to Low: Blastomyces, Histoplasma, and Coccidioides
Turnaround Time
Results Released: 72 hours
*New positives may require confirmationReference Range
Antibody not detected
Interpretative Information
Negative: Antibody not detected
Positive: Antibody detectedSpecimen Collection
- Specimen: Serum
- Uncommon Specimen: CSF, Plasma
Container:
- Serum: Submit serum in a separator or transfer tube..
- CSF/Plasma: Submit CSF/Plasma in a sterile leak-proof container.
Minimum Specimen Requirements
Volume: 0.25 mL
Specimen Stability
- Room temperature: 28 days
- Refrigerated: 6 months
- Frozen: indefinite
Specimen Rejection
Any specimen types other than serum, CSF, plasma
Transport Temperature
Refrigerated/Frozen
Shipping
Ship overnight with a cold pack.
* New positives may require confirmation.
** Turnaround times are provided as ranges, and may vary depending on daily testing volumes and specimen type.
*** Test set up: Samples received by 10:30AM will have same-day test set up. Positive samples may require confirmation which may extend turnaround time. Serum & CSF specimens are pretreated to improve sensitivity which can add one day to turnaround time.