Histoplasma Antigen EIA
- Test Information
- Specimen Requirements
- Shipping Information
Test Code
310
Clinical Significance
The MVista® Histoplasma Quantitative EIA test aids in the diagnosis of histoplasmosis. Monitoring the Histoplasma antigen helps to determine when treatment can be stopped and to diagnose relapse.
Methodology
- Quantitative Sandwich Enzyme Immunoassay (EIA)
- Serum and CSF are pre-treated to improve accuracy
Limitations
The result is not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Cross Reactivity/False Positive:- Very High: Blastomyces, Paracoccidioides and Talaromyces (talaromycosis, previously penicilliosis)
- Moderate: Coccidioides
- Rare: Aspergillus
- None: Cryptococcus
- Sputolysin, sodium hydroxide and potassium hydroxide treatment degrade the analyte detected in the assay.
Turnaround Time
Testing is performed Monday – Saturday.
Results released: 12 – 24 hours
* New positives may require confirmation
** Turnaround times are provided as ranges, and may vary depending on daily testing volumes and specimen type.
*** Test set up: Samples received by 10:30AM will have same-day test set up. Positive samples may require confirmation which may extend turnaround time. Serum & CSF specimens are pretreated to improve sensitivity which can add one day to turnaround time.
Reference Range
None detected
Interpretative Information
EIA New Test Parameters
- Reference Interval: None Detected
- Reportable Range: 0.2 ng/ml – 20.0 ng/ml
- Results above 20.0 ng/ml are reported as Positive, Above the Limit of Qualification
Additional Information
MVista® is a registered trademark of MiraVista Diagnostics
Specimen Collection
Specimen: Urine, Serum, Plasma, CSF, BAL
Anticoagulant: Heparin, EDTA, NaCit
Container:
Serum/Plasma: Submit serum and plasma in a separator or transfer tube.
Urine/CSF/BAL/Other Body Fluids: Submit urine, CSF, BAL or any other body fluids in a leak-proof container.Minimum Specimen Requirements
Volume: 0.8 mL
Specimen Stability
- Room Temperature: 14 days
- Refrigerated: 14 days
- Frozen: indefinite
Specimen Rejection
- If specimen is too viscous to pipette
- Tissue, Sputum, Bronchial Brushings, Stool, FNA, Biopsy, Tracheal or Bone Marrow Aspirate
- Stored in Transport Media, Fixative or Isolator Tubes
Transport Temperature
Refrigerated/Frozen/Room Temperature
Shipping
Ship Overnight or 2nd day ambient
* New positives may require confirmation.
** Turnaround times are provided as ranges, and may vary depending on daily testing volumes and specimen type.
*** Test set up: Samples received by 10:30AM will have same-day test set up. Positive samples may require confirmation which may extend turnaround time. Serum & CSF specimens are pretreated to improve sensitivity which can add one day to turnaround time.