Aspergillus Galactomannan Antigen EIA

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The Aspergillus antigen EIA test aids in the diagnosis of systemic aspergillosis in animals. This test has low sensitivity in dogs with sino-nasal aspergillosis; therefore, the test is not recommended for screening in those cases.

Platelia™ Aspergillus EIA immunoenzymatic sandwich microplate assay, cleared by the FDA for the detection of galactomannan in serum or BALF.

The result is not intended to be used as the sole means for clinical diagnosis or patient management decisions.

• – Antifungal therapy may cause false negative results in patients with aspergillosis.
• – Low positive results (0.5-1.5 GMI) are equivocal and may represent false positives, as the cutoff of 0.5 GMI was determined based on human studies for the early diagnosis of invasive fungal infections.
• – False positives can be caused by:

> Piperacillin-tazobactam, amoxicillin/clavulanic acid
> PLASMA-LYTE and other fluids containing sodium gluconate
> Infection with Penicillium, Alternaria, Paecilomyces, Fusarium, Histoplasma and Blastomyces, or airway colonization with above organisms

• Serum: Collect serum specimens in serum separator or red top tube. Allow blood to clot for 30 minutes, then centrifuge. Pipette serum into a plastic screw cap vial.
• Urine/CSF/BAL: Submit CSF and BAL in a sterile screw cap container.

Serum/Urine/CSF/BAL: 0.8 mL

• Room Temperature: 48 hours
• Refrigerated: 5 days
• Frozen: 5 months

If specimen is too viscous to pipette.

Refrigerated/Frozen

Ship on dry ice or frozen packs for next day service. Monday-Friday delivery

Serum/CSF/BAL: Same day

*New positives may require confirmation

Negative

• Negative: <0.5

*Results are reported as numeric values (Index) which are interpreted as positive or negative.

Platelia™ is a registered trademark of BioRad.