Aspergillus Antibody Immunodiffusion

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The Aspergillus Antibody Immunodiffusion test is used for the in vitro determination of precipitating antibodies to Aspergillus spp. The test is most useful in assisting with the diagnosis of sino-nasal aspergillosis in dogs.

Fungal Immunodiffusion

The result is not intended to be used as the sole means for clinical diagnosis or patient management decisions.

• Negative serologic tests may be observed among culturally demonstrable cases, which limits the predictive value of a negative test.
• Negative serologic results obtained during the first month may warrant repeat testing.
• Falsely negative results may be obtained when testing immunocompromised patients.
• Test results cannot be used solely to distinguish between active infection and prior exposure.
• C-Reactive Protein present in the patient’s serum may interfere with interpretation of results.

Cross Reactivity/False Positive: Moderate to Low: Blastomyces, Histoplasma, and Coccidioides

Testing performed Tuesday and Friday.
Results Released: Positive: 24 hours; Negative: 72 hours.

Antibody not detected

Negative: Antibody not detected
Positive: Antibody detected

Specimens:  Serum, CSF*, Plasma*
*Uncommon specimen includes incomplete validation. A “rare specimen” note will appear on the final report.

Container:
Serum: Collect serum specimens in serum separator tube. Allow blood to clot for 30 minutes, then centrifuge. Send in serum separator tube or transfer tube.
CSF, Plasma: Submit CSF and plasma in a leak-proof plastic tube.

Volume: 0.25mL
Stability: Room temperature = 28 days, Refrigerated = 6 months, Frozen = indefinite

Any specimen types other than serum, CSF, plasma

Refrigerated/Frozen

Ship overnight with a cold pack.