Beta-D-Glucan Antigen
- Test Information
- Specimen Requirements
- Shipping Information
Test Code
317
Clinical Significance
The Fungitell® assay measures the presence of (1→3)-β-D-Glucan in serum and CSF. Serum is the only specimen type cleared by the FDA for this assay. Performance characteristics of CSF have been validated by MiraVista Diagnostics.
Methodology
Colorimetric Fungitell® assay utilizing a (1→3)-β-D-Glucan -specific Limulus Amebocyte Lysate (LAL) reagent.
Limitations
Interfering Substance: Turbid or grossly discolored samples due to lipid, bilirubin, or hemolysis. Significantly elevated immunoglobulin concentrations.
Cross Reactivity/False Positive:- Hemodialysis
- Penicillin antibiotics
- Fractionated blood products (serum albumin and immunoglobulins)
- Specimens exposed to gauze or paper wipes
Turnaround Time
Testing is performed Monday – Friday.
Results released: 24 – 48 hours
Reference Range
None detected
Interpretative Information
Negative: <60 pg/mL
Indeterminate: 60 pg/mL – 79 pg/mL
Positive: 80 pg/mL – >500 pg/mLAdditional Information
* Fungitell® is a registered trademark of Associates of Cape Cod Inc.
Specimen Collection
Specimen: Serum, CSF
Container:
Serum: Collect serum specimens in serum separator tube. Allow blood to clot for 30 minutes, then centrifuge. Send in serum separator tube or pipette serum into a transport tube
CSF: Submit CSF in a sterile leak-proof plastic tube.Volume: 0.25 mL
Stability: Refrigerated = 5 days; Frozen = indefiniteSpecimen Rejection
Turbid or grossly discolored samples due to lipid, bilirubin, or hemolysis or significantly elevated immunoglobulin concentrations may be rejected due to interference.
Transport Temperature
Refrigerated/Frozen
Shipping
Ship overnight with a cold pack.