Peer-Reviewed Publications

Antifungal Therapy

• Therapeutic Drug Monitoring of Itraconazole in Dogs and Cats. 2017 February
• Goughenour KD and CA Rappleye. Antifungal therapeutics for dimorphic fungal pathogens. Virulence 2017; 8(2):211-21.
• Middleton SM et al. Alternate-day dosing of itraconazole in healthy adult cats. J Vet Pharmacol Therap 2016; 39(1): 27-31.
• Mawby DI et al. Bioequivalence of orally administered generic, compounded, and innovator-formulated itraconazole in healthy dogs. JVIM 2014;28(1):72-7.
• Santos JR et al. Dynamic interaction between fluconazole and amphotericin B against Cryptococcus gattii. Antimicrob Agents Chemother 2012;56(5):2553-8.
• Mazepa AS, LA Trepanier and DS Foy. Retrospective comparison of the efficacy of fluconazole or itraconazole for the treatment of systemic blastomycosis in dogs. JVIM 2011;25(3):440-5.
• Smith JA et al. Effects of compounding on pharmacokinetics of itraconazole in black-footed penguins (Spheniscus demersus). J Zoo Wildlife Med 2010;41(3):487-95.
• Foy DS and LA Trepanier. Antifungal treatment of small animal veterinary patients. Vet Clin Small Anim 2010; 40(6):1171-88.
• Wheat LJ et al. Emergence of resistance to fluconazole as a cause of failure during treatment of histoplasmosis in patients with acquired immunodeficiency disease syndrome. CID 2001;33(11):1910-3.
• Lemonte AM et al. Amphotericin B combined with itraconazole or fluconazole for treatment of histoplasmosis. J Infect Dis 2000;182(2):545-50.
• Wheat LJ et al. Hypothesis on the mechanism of resistance to fluconazole in Histoplasma capsulatum. Antimicrob Agents Chemother 1997;41(2):410-4.

Sinonasal Aspergillosis

• Whitney J et al. Evaluation of serum galactomannan detection for diagnosis of feline upper respiratory tract aspergillosis. Vet Microbiol 2013;162(1):180-5.
• Barrs VR et al. Sinonasal and sino-orbital aspergillosis in 23 cats: Aetiology, clinicopathological features and treatment outcomes. Vet J 2012;191(1):58-64.
• Billen F et al. Comparison of the value of measurement of serum galactomannan and Aspergillus-specific antibodies in the diagnosis of canine sino-nasal aspergillosis. Vet Microbiol 2009;133(4):358-65.
• Pomrantz JS et al. Comparison of serologic evaluation via agar gel immunodiffusion and fungal culture of tissue for diagnosis of nasal aspergillosis in dogs. JAVMA 2007;230(9):1319-23.

Systemic Aspergillosis

• Corrigan VK et al. Treatment of disseminated aspergillosis with posaconazole in 10 dogs. JVIM 2016;30(1):167-73.
• Barrs VR et al. Aspergillus felis nov., an emerging agent of invasive aspergillosis in humans, cats, and dogs. PLoS One 2013;8(6):e64871.
• Garcia RS et al. Sensitivity and specificity of a blood and urine galactomannan antigen assay for diagnosis of systemic aspergillosis in dogs. JVIM 2012;26(4):911-9.

Blastomycosis

• Mourning AC, EE Patterson, EJ Kirsch, et al. Evaluation of an enzyme immunoassay for antibodies to a recombinant Blastomyces adhesin-1 repeat antigen as an aid in the diagnosis of blastomycosis in dogs. JAVMA 2015;247(10):1133-8.
• Richer SM, ML Smedema, MM Durkin, et al. Development of a highly sensitive and specific blastomycosis antibody enzyme immunoassay using Blastomyces dermatitidis surface protein BAD-1. CVI 2014;21(2):143-6.
• Panciera DL, GC Troy and BJ Purswell. Blastomycosis in a postpartum dog. Med Mycol Case Reports 2014;6:29-30.
• Anderson JL, JL Dieckman, KD Reed, et al. Canine blastomycosis in Wisconsin: A survey of small-animal veterinary practices. Med Mycol 2014;52(7):774-9.
• Foy DS, LA Trepanier, EJ Kirsch, et al. Serum and urine blastomyces antigen concentrations as markers of clinical remission in dogs treated for systemic blastomycosis. JVIM 2014;28(2):305-10.
• Serum and Urine Blastomyces Antigen Concentrations as Markers of Clinical Remission in Dogs Treated for Systemic Blastomycosis: Journal of Veterinary Internal Medicine, 2014
• Mazepa AS, LA Trepanier and DS Foy. Retrospective comparison of the efficacy of fluconazole or itraconazole for the treatment of systemic blastomycosis in dogs. JVIM 2011;25(3):440-5.
• Antigen and Antibody Testing for the Diagnosis of Blastomycosis in Dogs: Journal of Veterinary Internal Medicine, 2008, p. 839-843
• Spector D, AM Legendre, J Wheat, et al. Antigen and antibody testing for the diagnosis of blastomycosis in dogs. JVIM 2008;22(4):839-43.
• Wilson JH, EJ Olson, EW Haugen, et al. Systemic blastomycosis in a horse. J Vet Diagn Invest 2006;18(6):615-9.
• Treatment of Blastomycosis With Itraconazole in 112 Dogs: Journal of Veterinary Internal Medicine, Volume 10, No. 6 (November-December 1996), p. 365-371
• Legendre AM, BW Rohrbach, RL Toal, et al. Treatment of blastomycosis with itraconazole in 112 dogs. JVIM 1996;10(6):365-71.

Coccidioidomycosis

• Hanzlicek AS, Meinkoth JH, Renschler JS, Goad C, Wheat LJ. Antigen Concentrations as an Indicator of Clinical Remission and Disease Relapse in Cats with Histoplasmosis. J Vet Intern Med. 2016 Jul;30(4):1065-73.
• Kirsch EJ, RT Greene, A Prahl, et al. Evaluation of Coccidioides antigen detection in dogs with coccidioidomycosis. Clin Vaccine Immunol 2012;19(3):343-5.

Histoplasmosis

• Renschler JS, Norsworthy GD, Rakian RA, Rakian AI, Wheat LJ, Hanzlicek AS. Reduced susceptibility to fluconazole in a cat with histoplasmosis. JFMS Open Rep. 2017 Nov 28;3(2):2055116917743364. doi: 10.1177/2055116917743364. eCollection 2017 Jul-Dec.
• Hanzlicek AS, Meinkoth JH, Renschler JS, Goad C, Wheat LJ. Antigen concentrations as an indicator of clinical remission and disease relapse in cats with histoplasmosis. J Vet Intern Med. 2016 Jul;30(4):1065-73.
• Cook AK, Cunningham LY, Cowell AK, Wheat LJ. Clinical evaluation of urine Histoplasma capsulatum antigen measurement in cats with suspected disseminated histoplasmosis. J Feline Med Surg. 2012 Aug;14(8):512-5.
• Development of an enzyme immunoassay for detection of antibodies against Coccidioides in dogs and other mammalian species.Chow NA, Lindsley MD, McCotter OZ, Kangiser D, Wohrle RD, Clifford WR, Yaglom HD, Adams LE, Komatsu K, Durkin MM, Baker RJ, Shubitz LF, Derado G, Chiller TM, Litvintseva AP. PLoS One. 2017 Apr 5;12(4):e0175081. doi: 10.1371/journal.pone.0175081. eCollection 2017.
• Clinical Evaluation of Urine Histoplasma capsulatum Antigen Measurement in Cats with Suspected Disseminated Histoplasmosis: Journal of Feline Medicine and Surgery, May 2012